Transient Production of therapeutic compounds
| Project start date: | 20 May 2011 |
| Project end date: | 07 September 2012 |
| Publication date: | 01 September 2012 |
| Project status: | Terminated |
| Livestock species: | Sheep, Goat, Lamb, Grassfed cattle, Grainfed cattle |
| Relevant regions: | National |
|
Download Report
(0.4 MB)
|
|
Summary
Background
These projects aimed to develop a new bioprocess that amplifies yields of commercially valuable bioactive products from 'farmed' animal organs.
Research
The first project (A.BIT.0008) aimed to develop new bioprocesses by amplification of the yields of commercially valuable bioactive products from cultured animal organs. In phase 1 of this project, up to 43-fold amplification of the levels of certain bioactives was reported in small- scale laboratory trials. Phase 2 focused on scale-up to commercially competitive levels using alkaline phosphatase (AP) as a model bioactive. An external consultant, Dr Gareth Forde, analysed the production process and generated an engineering-based economic model and sensitivity analysis for the manufacture of bioactives using the organ culture method developed.
Outcomes
The detailed technical and cost benefit analysis concluded that the technology was neither commercially or technically viable, and further investment was terminated by MLA.
More information
| Project manager: | Rajesh Margapuram |
| Primary researcher: | Flinders University |
